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Translesion Synthesis past Equine Estrogen-derived 2′-Deoxyadenosine DNA adducts by Human DNA polymerases η and κ
Hormone replacement therapy (HRT) increases the risk of developing breast, ovarian and endometrial cancers. Equilin and equilenin are the major components of the widely prescribed drug used for HRT. 4-hydroxyequilenin (4-OHEN), a major metabolite of equilin and equilenin, promotes 4-OHEN-modified dC...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2504361/ https://ncbi.nlm.nih.gov/pubmed/16681391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0525324 |
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