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The Csk-binding protein PAG regulates PDGF-induced Src mitogenic signaling via GM1

Spatial regulation is an important feature of signal specificity elicited by cytoplasmic tyrosine kinases of the Src family (SRC family protein tyrosine kinases [SFK]). Cholesterol-enriched membrane domains, such as caveolae, regulate association of SFK with the platelet-derived growth factor recept...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Veracini, Laurence, Simon, Valérie, Richard, Véronique, Schraven, Burkhart, Horejsi, Vaclav, Roche, Serge, Benistant, Christine
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2500143/
https://ncbi.nlm.nih.gov/pubmed/18695048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200705102
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