The Csk-binding protein PAG regulates PDGF-induced Src mitogenic signaling via GM1

Spatial regulation is an important feature of signal specificity elicited by cytoplasmic tyrosine kinases of the Src family (SRC family protein tyrosine kinases [SFK]). Cholesterol-enriched membrane domains, such as caveolae, regulate association of SFK with the platelet-derived growth factor recept...

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Detalhes bibliográficos
Main Authors: Veracini, Laurence, Simon, Valérie, Richard, Véronique, Schraven, Burkhart, Horejsi, Vaclav, Roche, Serge, Benistant, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2500143/
https://ncbi.nlm.nih.gov/pubmed/18695048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200705102
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