The Tom1L1-Clathrin Heavy Chain Complex Regulates Membrane Partitioning of the Tyrosine Kinase Src Required for Mitogenic and Transforming Activities

Compartmentalization of Src tyrosine kinases (SFK) plays an important role in signal transduction induced by a number of extracellular stimuli. For example, Src mitogenic signaling induced by platelet-derived growth factor (PDGF) is initiated in cholesterol-enriched microdomain caveolae. How this Sr...

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Bibliographic Details
Main Authors: Collin, Guillaume, Franco, Mélanie, Simon, Valérie, Bénistant, Christine, Roche, Serge
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2007
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169060/
https://ncbi.nlm.nih.gov/pubmed/17785434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00543-07
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