FGF-23–Klotho signaling stimulates proliferation and prevents vitamin D–induced apoptosis

Fibroblast growth factor 23 (FGF-23) and Klotho are secretory proteins that regulate mineral-ion metabolism. Fgf-23(−/−) or Klotho(−/−) knockout mice exhibit several pathophysiological processes consistent with premature aging including severe atrophy of tissues. We show that the signal transduction...

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Detalhes bibliográficos
Main Authors: Medici, Damian, Razzaque, Mohammed S., DeLuca, Stephelynn, Rector, Trent L., Hou, Bo, Kang, Kihwa, Goetz, Regina, Mohammadi, Moosa, Kuro-o, Makoto, Olsen, Bjorn R., Lanske, Beate
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2500132/
https://ncbi.nlm.nih.gov/pubmed/18678710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200803024
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