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Increased chemotactic migration and growth in heparanase-overexpressing human U251n glioma cells

Heparanase is an endoglycosidase that degrades heparan sulfate, the main polysaccharide constituent of the extracellular matrix (ECM) and basement membrane. Expression of the heparanase gene is associated with the invasion and metastatic potential of a variety of tumor-derived cell types. However, t...

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Bibliografische gegevens
Hoofdauteurs: Hong, Xin, Jiang, Feng, Kalkanis, Steven N, Zhang, Zheng Gang, Zhang, Xuepeng, Zheng, Xuguang, Jiang, Hao, Mikkelsen, Tom, Chopp, Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2499998/
https://ncbi.nlm.nih.gov/pubmed/18647407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-27-23
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