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Intracellular free calcium mediates glioma cell detachment and cytotoxicity after photodynamic therapy

Photofrin photodynamic therapy (PDT) caused a dose-dependent decrease of enzymatic cell detachment by trypsin/ethylenediamine tetra-acetic acid (EDTA) in human glioma U251n and U87 cells. This happened coincidently with the increase of intracellular free calcium ([Ca(2+)](i)). Thapsigargin, which in...

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Detalhes bibliográficos
Main Authors: Hong, Xin, Jiang, Feng, Kalkanis, Steven N., Zhang, Zheng Gang, Zhang, Xuepeng, Zheng, Xuguang, Jiang, Hao, Chopp, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746241/
https://ncbi.nlm.nih.gov/pubmed/19198972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10103-008-0640-5
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