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Reductive Activation of Hexavalent Chromium by Human Lung Epithelial Cells: Generation of Cr(V) and Cr(V)-Thiol Species
Chromium(VI) compounds (e.g. chromates) are cytotoxic, mutagenic, and potentially carcinogenic. The reduction of Cr(VI) can yield reactive intermediates such as Cr(V) and reactive oxygen species. Bronchial epithelial cells are the primary site of pulmonary exposure to inhaled Cr(VI) and are the prim...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2497427/ https://ncbi.nlm.nih.gov/pubmed/18279960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2007.12.030 |
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