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Reduction of Hexavalent Chromium by Human Cytochrome b(5): Generation of Hydroxyl Radical and Superoxide

The reduction of hexavalent chromium, Cr(VI), can generate reactive Cr intermediates and various types of oxidative stress. The potential role of human microsomal enzymes in free radical generation was examined using reconstituted proteoliposomes (PLs) containing purified cytochrome b(5) and NADPH:P...

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Detalhes bibliográficos
Main Authors: Borthiry, Griselda R., Antholine, William E., Kalyanaraman, B., Myers, Judith M., Myers, Charles R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1993546/
https://ncbi.nlm.nih.gov/pubmed/17320757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2006.10.055
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