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Nonmuscle myosin II-B is required for normal development of the mouse heart

We used targeted gene disruption in mice to ablate nonmuscle myosin heavy chain B (NMHC-B), one of the two isoforms of nonmuscle myosin II present in all vertebrate cells. Approximately 65% of the NMHC-B(−/−) embryos died prior to birth, and those that were born suffered from congestive heart failur...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Tullio, Antonella N., Accili, Domenico, Ferrans, Victor J., Yu, Zu-Xi, Takeda, Kazuyo, Grinberg, Alexander, Westphal, Heiner, Preston, Yvette A., Adelstein, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1997
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24969/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9356462/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.23.12407
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