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Nonmuscle myosin II-B is required for normal development of the mouse heart
We used targeted gene disruption in mice to ablate nonmuscle myosin heavy chain B (NMHC-B), one of the two isoforms of nonmuscle myosin II present in all vertebrate cells. Approximately 65% of the NMHC-B(−/−) embryos died prior to birth, and those that were born suffered from congestive heart failur...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC24969/ https://ncbi.nlm.nih.gov/pubmed/9356462 |
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