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Lamin A/C Is a Risk Biomarker in Colorectal Cancer

BACKGROUND: A-type lamins are type V intermediate filament proteins encoded by the gene LMNA. Mutations in LMNA give rise to diverse degenerative diseases related to premature ageing. A-type lamins also influence the activity of the Retinoblastoma protein (pRb) and oncogenes such a β-catenin. Conseq...

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Detaylı Bibliyografya
Asıl Yazarlar: Willis, Naomi D., Cox, Thomas R., Rahman-Casañs, Syed F., Smits, Kim, Przyborski, Stefan A., van den Brandt, Piet, van Engeland, Manon, Weijenberg, Matty, Wilson, Robert G., de Bruïne, Adriaan, Hutchison, Christopher J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2496895/
https://ncbi.nlm.nih.gov/pubmed/18714339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002988
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