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Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of the central zinc-binding domain of the human Mcm10 DNA-replication factor

The initiation of eukaryotic DNA replication requires the tightly controlled assembly of a set of replication factors. Mcm10 is a highly conserved nuclear protein that plays a key role in the initiation and elongation processes of DNA replication by providing a physical link between the Mcm2–7 compl...

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Autori principali: Jung, Nam Young, Bae, Won Jin, Chang, Jeong Ho, Kim, Young Chang, Cho, Yunje
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2496859/
https://ncbi.nlm.nih.gov/pubmed/18540058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108011640
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