The guanine-nucleotide-exchange factor BopE from Burkholderia pseudomallei adopts a compact version of the Salmonella SopE/SopE2 fold and undergoes a closed-to-open conformational change upon interaction with Cdc42

BopE is a type III secreted protein from Burkholderia pseudomallei, the aetiological agent of melioidosis, a severe emerging infection. BopE is a GEF (guanine-nucleotide-exchange factor) for the Rho GTPases Cdc42 (cell division cycle 42) and Rac1. We have determined the structure of BopE catalytic d...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Upadhyay, Abhishek, Wu, Huan-Lin, Williams, Christopher, Field, Terry, Galyov, Edouard E., Van Den ELSEN, Jean M. H., Bagby, Stefan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2495041/
https://ncbi.nlm.nih.gov/pubmed/18052936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20071546
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky