A Burkholderia pseudomallei Type III Secreted Protein, BopE, Facilitates Bacterial Invasion of Epithelial Cells and Exhibits Guanine Nucleotide Exchange Factor Activity

We report the characterization of BopE, a type III secreted protein that is encoded adjacent to the Burkholderia pseudomallei bsa locus and is homologous to Salmonella enterica SopE/SopE2. Inactivation of bopE impaired bacterial entry into HeLa cells, indicating that BopE facilitates invasion. Consi...

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Detalhes bibliográficos
Main Authors: Stevens, Mark P., Friebel, Andrea, Taylor, Lowrie A., Wood, Michael W., Brown, Philip J., Hardt, Wolf-Dietrich, Galyov, Edouard E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Molecular Biology of Pathogens
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC166480/
https://ncbi.nlm.nih.gov/pubmed/12897019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.16.4992-4996.2003
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