The guanine-nucleotide-exchange factor BopE from Burkholderia pseudomallei adopts a compact version of the Salmonella SopE/SopE2 fold and undergoes a closed-to-open conformational change upon interaction with Cdc42

BopE is a type III secreted protein from Burkholderia pseudomallei, the aetiological agent of melioidosis, a severe emerging infection. BopE is a GEF (guanine-nucleotide-exchange factor) for the Rho GTPases Cdc42 (cell division cycle 42) and Rac1. We have determined the structure of BopE catalytic d...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Upadhyay, Abhishek, Wu, Huan-Lin, Williams, Christopher, Field, Terry, Galyov, Edouard E., Van Den ELSEN, Jean M. H., Bagby, Stefan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2495041/
https://ncbi.nlm.nih.gov/pubmed/18052936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20071546
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares