Determinants of Sensitivity of Human T Cell Leukemia CCRF-CEM cells to Immucillin-H

Immucillin-H (BCX-1777, forodesine) is a transition state analogue and potent inhibitor of PNP that shows promise as a specific agent against activated human T-cells and T-cell leukemias. The immunosuppressive or antileukemic effects of Immucillin-H (ImmH) require co-administration with deoxyguanosi...

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Bibliografiset tiedot
Päätekijät: Huang, Min, Wang, Yanhong, Gu, Jingjin, Yang, Jing, Noel, Karen, Mitchell, Beverly S., Schramm, Vern L., Graves, Lee M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494856/
https://ncbi.nlm.nih.gov/pubmed/18279955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2007.12.015
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