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Determinants of Sensitivity of Human T Cell Leukemia CCRF-CEM cells to Immucillin-H
Immucillin-H (BCX-1777, forodesine) is a transition state analogue and potent inhibitor of PNP that shows promise as a specific agent against activated human T-cells and T-cell leukemias. The immunosuppressive or antileukemic effects of Immucillin-H (ImmH) require co-administration with deoxyguanosi...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2494856/ https://ncbi.nlm.nih.gov/pubmed/18279955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2007.12.015 |
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