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Differences in STIM1 and TRPC expression in proximal and distal pulmonary arterial smooth muscle are associated with differences in Ca(2+) responses to hypoxia

Hypoxic pulmonary vasoconstriction (HPV) requires Ca(2+) influx through store-operated Ca(2+) channels (SOCC) in pulmonary arterial smooth muscle cells (PASMC) and is greater in distal than proximal pulmonary arteries (PA). SOCC may be composed of canonical transient receptor potential (TRPC) protei...

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Autors principals: Lu, Wenju, Wang, Jian, Shimoda, Larissa A., Sylvester, J. T.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494791/
https://ncbi.nlm.nih.gov/pubmed/18424621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00058.2008
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