Hemagglutinin mutations related to attenuation and altered cell tropism of a virulent avian influenza A virus.

The H5 hemagglutinin (HA) of a highly virulent avian influenza virus, A/Turkey Ontario/7732/66 (H5N9), was previously shown to have five neutralizing epitopes, and escape mutants within one epitope (group 1) were markedly attenuated (M. Philpott, B. C. Easterday, and V. S. Hinshaw, J. Virol. 63:3453...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Philpott, M, Hioe, C, Sheerar, M, Hinshaw, V S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249478/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2335822/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.6.2941-2947.1990
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