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Hemagglutinin mutations related to attenuation and altered cell tropism of a virulent avian influenza A virus.

The H5 hemagglutinin (HA) of a highly virulent avian influenza virus, A/Turkey Ontario/7732/66 (H5N9), was previously shown to have five neutralizing epitopes, and escape mutants within one epitope (group 1) were markedly attenuated (M. Philpott, B. C. Easterday, and V. S. Hinshaw, J. Virol. 63:3453...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Philpott, M, Hioe, C, Sheerar, M, Hinshaw, V S
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1990
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249478/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2335822/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.6.2941-2947.1990
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