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Hemagglutinin mutations related to attenuation and altered cell tropism of a virulent avian influenza A virus.

The H5 hemagglutinin (HA) of a highly virulent avian influenza virus, A/Turkey Ontario/7732/66 (H5N9), was previously shown to have five neutralizing epitopes, and escape mutants within one epitope (group 1) were markedly attenuated (M. Philpott, B. C. Easterday, and V. S. Hinshaw, J. Virol. 63:3453...

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Publicado en:J Virol
Autores principales: Philpott, M, Hioe, C, Sheerar, M, Hinshaw, V S
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1990
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249478/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2335822/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.6.2941-2947.1990
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