Hemagglutinin mutations related to attenuation and altered cell tropism of a virulent avian influenza A virus.

The H5 hemagglutinin (HA) of a highly virulent avian influenza virus, A/Turkey Ontario/7732/66 (H5N9), was previously shown to have five neutralizing epitopes, and escape mutants within one epitope (group 1) were markedly attenuated (M. Philpott, B. C. Easterday, and V. S. Hinshaw, J. Virol. 63:3453...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Philpott, M, Hioe, C, Sheerar, M, Hinshaw, V S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1990
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249478/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2335822/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.6.2941-2947.1990
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