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Cyclic AMP acts through Rap1 and JNK signaling to increase expression of cutaneous smooth muscle α(2C)-adrenoceptors
Cold increases cutaneous vasoconstriction by unmasking the contractile activity of α(2C)-adrenoceptors (α(2C)-ARs) in vascular smooth muscle cells (VSMCs), which is mediated by the cold-induced mobilization of α(2C)-ARs from the transGolgi to the cell surface. The expression of α(2C)-ARs in human cu...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2494767/ https://ncbi.nlm.nih.gov/pubmed/18487435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00084.2008 |
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