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Cyclic AMP-Rap1A signaling mediates cell surface translocation of microvascular smooth muscle α(2C)-adrenoceptors through the actin-binding protein filamin-2
The second messenger cyclic AMP (cAMP) plays a vital role in vascular physiology, including vasodilation of large blood vessels. We recently demonstrated cAMP activation of Epac-Rap1A and RhoA-Rho-associated kinase (ROCK)-F-actin signaling in arteriolar-derived smooth muscle cells increases expressi...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3798683/ https://ncbi.nlm.nih.gov/pubmed/23864608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00221.2012 |
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