Cyclic AMP-mediated regulation of vascular smooth muscle cell cyclic AMP phosphodiesterase activity

1. Rat cultured aortic vascular smooth muscle cells (VSMC) express both cyclic GMP-inhibited cyclic AMP phosphodiesterase (PDE3) and Ro 20-1724-inhibited cyclic AMP phosphodiesterase (PDE4) activities. By utilizing either cilostamide, a PDE3-selective inhibitor, or Ro 20-1724, a PDE4-selective inhib...

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Bibliographic Details
Main Authors: Rose, R J, Liu, H, Palmer, D, Maurice, D H
Format: Artigo
Language:Inglês
Published: 1997
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Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564933/
https://ncbi.nlm.nih.gov/pubmed/9313930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701376
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