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ACTH-induced hypertension is dependent on the ouabain-binding site of the α(2)-Na(+)-K(+)-ATPase subunit

ACTH-induced-hypertension is commonly employed as a model of stress-related hypertension, and despite extensive investigation, the mechanisms underlying elevated blood pressure (BP) are not well understood. We have reported that ACTH treatment increases tail-cuff systolic pressure in wild-type mice...

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Autors principals: Lorenz, John N., Loreaux, Elizabeth L., Dostanic-Larson, Iva, Lasko, Valerie, Schnetzer, J. Renee, Paul, Richard J., Lingrel, Jerry B
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494766/
https://ncbi.nlm.nih.gov/pubmed/18487447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00183.2008
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