Colonic gene expression profile in NHE3-deficient mice: evidence for spontaneous distal colitis

Na(+)/H(+) exchanger 3 (NHE3) provides a major route for intestinal Na(+) absorption. NHE3 has been considered a target of proinflammatory cytokines and enteropathogenic bacteria, and impaired NHE3 expression and/or activity may be responsible for inflammation-associated diarrhea. However, the possi...

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Autori principali: Laubitz, Daniel, Larmonier, Claire B., Bai, Aiping, Midura-Kiela, Monica T., Lipko, Maciej A., Thurston, Robert D., Kiela, Pawel R., Ghishan, Fayez K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2008
Soggetti:
Inflammation/Immunity/Mediators
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494721/
https://ncbi.nlm.nih.gov/pubmed/18467500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90207.2008
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