Obese Mice Lacking Inducible Nitric Oxide Synthase Are Sensitized to the Metabolic Actions of Peroxisome Proliferator–Activated Receptor-γ Agonism

OBJECTIVE—Synthetic ligands for peroxisome proliferator–activated receptor-γ (PPAR-γ) improve insulin sensitivity in obesity, but it is still unclear whether inflammatory signals modulate their metabolic actions. In this study, we tested whether targeted disruption of inducible nitric oxide (NO) syn...

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Bibliografski detalji
Glavni autori: Dallaire, Patrice, Bellmann, Kerstin, Laplante, Mathieu, Gélinas, Stéphanie, Centeno-Baez, Carolina, Penfornis, Patrice, Peyot, Marie-Line, Latour, Martin G., Lamontagne, Julien, Trujillo, Maria E., Scherer, Philipp E., Prentki, Marc, Deshaies, Yves, Marette, André
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2008
Teme:
Metabolism
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494686/
https://ncbi.nlm.nih.gov/pubmed/18458147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0540
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