A deletion in the Friend spleen focus-forming virus env gene is necessary for its product (gp55) to be leukemogenic.

To determine the biological significance of the 585-base-pair deletion in the env gene of Friend spleen focus-forming virus (SFFV) encoding a leukemogenic glycoprotein (gp55), we examined the pathogenicity of a constructed mutant SFFV (SFFVDF). In the SFFVDF genome, the env deletion was filled in wi...

Disgrifiad llawn

Manylion Llyfryddiaeth

Cyhoeddwyd yn:	J Virol
Prif Awduron:	Watanabe, N, Nishi, M, Ikawa, Y, Amanuma, H
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Microbiology (ASM) 1990
Pynciau:	Research Article
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249446/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2159537/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.6.2678-2686.1990
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!