A deletion in the Friend spleen focus-forming virus env gene is necessary for its product (gp55) to be leukemogenic.

To determine the biological significance of the 585-base-pair deletion in the env gene of Friend spleen focus-forming virus (SFFV) encoding a leukemogenic glycoprotein (gp55), we examined the pathogenicity of a constructed mutant SFFV (SFFVDF). In the SFFVDF genome, the env deletion was filled in wi...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Watanabe, N, Nishi, M, Ikawa, Y, Amanuma, H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1990
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249446/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2159537/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.6.2678-2686.1990
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