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The BRCA2 gene product functionally interacts with p53 and RAD51

Germ-line mutations in the human BRCA2 gene confer susceptibility to breast cancer. Efforts to elucidate its function have revealed a putative transcriptional activation domain and in vitro interaction with the DNA repair protein RAD51. Other studies have indicated that RAD51 physically associates w...

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Detalhes bibliográficos
Main Authors: Marmorstein, Lihua Y., Ouchi, Toru, Aaronson, Stuart A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC24938/
https://ncbi.nlm.nih.gov/pubmed/9811893
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