Ocular avirulence of a herpes simplex virus type 1 strain is associated with heightened sensitivity to alpha/beta interferon.

BALB/c mice infected on the scarified cornea with herpes simplex virus type 1 strain 35 [HSV-1(35)] rarely developed ocular disease even at challenge doses as high as 10(7) PFU per eye. In contrast, HSV-1(RE) consistently induced stromal keratitis at an inoculum of 2 x 10(4) PFU. The goal of this st...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Su, Y H, Oakes, J E, Lausch, R N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249378/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2157880/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.5.2187-2192.1990
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