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Mapping of helicase and helicase substrate-binding domains on simian virus 40 large T antigen.

We generated fragments of simian virus 40 large tumor antigen (T antigen) by tryptic digestion and assayed them for helicase activity and helicase substrate (mostly single-stranded DNA)-binding activity in order to map the domain sites on the protein. The N-terminal 130 amino acids were not required...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Wun-Kim, K, Simmons, D T
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1990
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249356/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2157869/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.5.2014-2020.1990
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