Four major sequence elements of simian virus 40 large T antigen coordinate its specific and nonspecific DNA binding.

By mutational analysis, we have identified a motif critical to the proper recognition and binding of simian virus 40 large tumor antigen (T antigen) to virus DNA sequences at the origin of DNA replication. This motif is tripartite and consists of two elements (termed A1 and B2) that are necessary fo...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Simmons, D T, Loeber, G, Tegtmeyer, P
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1990
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249351/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2157865/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.5.1973-1983.1990
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