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Fibroblast Growth Factor Signaling Uses Multiple Mechanisms To Inhibit Wnt-Induced Transcription in Osteoblasts

Fibroblast growth factor (FGF) and Wnt signals are both critical for proper bone development. We previously reported that the expression of activating FGF receptor mutations in osteoblasts downregulated the expression of many genes reported as targets of Wnt signaling, suggesting an antagonistic eff...

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Bibliografske podrobnosti
Main Authors: Ambrosetti, Davide, Holmes, Greg, Mansukhani, Alka, Basilico, Claudio
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493354/
https://ncbi.nlm.nih.gov/pubmed/18505824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01849-07
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