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Varicella-Zoster Virus Open Reading Frame 66 Protein Kinase Is Required for Efficient Viral Growth in Primary Human Corneal Stromal Fibroblast Cells

Varicella-zoster virus (VZV) open reading frame 66 (ORF66) encodes a serine/threonine protein kinase that is not required for VZV growth in most cell types but is needed for efficient growth in T cells. The ORF66 kinase affects nuclear import and virion packaging of IE62, the major regulatory protei...

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Detalhes bibliográficos
Main Authors: Erazo, Angela, Yee, Michael B., Osterrieder, Nikolaus, Kinchington, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493351/
https://ncbi.nlm.nih.gov/pubmed/18495764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00311-08
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