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Downregulation of Class I Major Histocompatibility Complex Surface Expression by Varicella-Zoster Virus Involves Open Reading Frame 66 Protein Kinase-Dependent and -Independent Mechanisms

We show here that the varicella-zoster virus (VZV) open reading frame 66 (ORF66) protein kinase is one mechanism employed to reduce class I major histocompatibility complex (MHC-I) surface expression in VZV-infected cells. Cells expressing enhanced green fluorescent protein-tagged functional and ina...

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Detalhes bibliográficos
Main Authors: Eisfeld, Amie J., Yee, Michael B., Erazo, Angela, Abendroth, Allison, Kinchington, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951447/
https://ncbi.nlm.nih.gov/pubmed/17567702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00711-07
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