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Deletion in Open Reading Frame 49 of Varicella-Zoster Virus Reduces Virus Growth in Human Malignant Melanoma Cells but Not in Human Embryonic Fibroblasts

The ORF49 gene product (ORF49p) of the varicella-zoster virus (VZV) is likely a myristylated tegument protein, and its homologs are conserved across the herpesvirus subfamilies. The UL11 gene of herpes simplex virus type 1 and of pseudorabies virus and the UL99 gene of human cytomegalovirus are the...

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Detalhes bibliográficos
Main Authors: Sadaoka, Tomohiko, Yoshii, Hironori, Imazawa, Takayoshi, Yamanishi, Koichi, Mori, Yasuko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169031/
https://ncbi.nlm.nih.gov/pubmed/17855513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01183-07
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