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Varicella-zoster virus ORF 58 gene is dispensable for viral replication in cell culture

BACKGROUND: Open reading frame 58 (ORF58) of varicella-zoster virus (VZV) lies at the 3'end of the Unique long (U(L)) region and its functional is unknown. In order to clarify whether ORF58 is essential for the growth of VZV, we constructed a deletion mutant of ORF58 (pOka-BACΔ58) from the Oka...

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Detalhes bibliográficos
Main Authors: Yoshii, Hironori, Sadaoka, Kay, Matsuura, Masaaki, Nagaike, Kazuhiro, Takahashi, Michiaki, Yamanishi, Koichi, Mori, Yasuko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2412858/
https://ncbi.nlm.nih.gov/pubmed/18445300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-5-54
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