A Live Attenuated Severe Acute Respiratory Syndrome Coronavirus Is Immunogenic and Efficacious in Golden Syrian Hamsters

The immunogenicity and protective efficacy of a live attenuated vaccine consisting of a recombinant severe acute respiratory syndrome (SARS) coronavirus lacking the E gene (rSARS-CoV-ΔE) were studied using hamsters. Hamsters immunized with rSARS-CoV-ΔE developed high serum-neutralizing antibody tite...

Full description

Saved in:
Bibliographic Details
Main Authors: Lamirande, Elaine W., DeDiego, Marta L., Roberts, Anjeanette, Jackson, Jadon P., Alvarez, Enrique, Sheahan, Tim, Shieh, Wun-Ju, Zaki, Sherif R., Baric, Ralph, Enjuanes, Luis, Subbarao, Kanta
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493341/
https://ncbi.nlm.nih.gov/pubmed/18463152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00304-08
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items