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Recombinant Adeno-Associated Viral Vectors Are Deficient in Provoking a DNA Damage Response
Adeno-associated virus type 2 (AAV2) provokes a DNA damage response that mimics a stalled replication fork. We have previously shown that this response is dependent on ataxia telangiectasia-mutated and Rad3-related kinase and involves recruitment of DNA repair proteins into foci associated with AAV2...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2493315/ https://ncbi.nlm.nih.gov/pubmed/18463154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00358-08 |
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