Shiga Toxin 2 Causes Apoptosis in Human Brain Microvascular Endothelial Cells via C/EBP Homologous Protein

Shiga toxin 1 (Stx1) and Stx2 produced by Escherichia coli O157 are known to be cytotoxic to Vero and HeLa cells by inhibiting protein synthesis and by inducing apoptosis. In the present study, we have demonstrated that 10 ng/ml Stx2 induced DNA fragmentation in human brain microvascular endothelial...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fujii, Jun, Wood, Katie, Matsuda, Fumiko, Carneiro-Filho, Benedito A., Schlegel, Keilo H., Yutsudo, Takashi, Binnington-Boyd, Beth, Lingwood, Clifford A., Obata, Fumiko, Kim, Kwang S., Yoshida, Shin-ichi, Obrig, Tom
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2008
Pynciau:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493216/
https://ncbi.nlm.nih.gov/pubmed/18541659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01581-07
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