Shiga Toxin 2 Causes Apoptosis in Human Brain Microvascular Endothelial Cells via C/EBP Homologous Protein

Shiga toxin 1 (Stx1) and Stx2 produced by Escherichia coli O157 are known to be cytotoxic to Vero and HeLa cells by inhibiting protein synthesis and by inducing apoptosis. In the present study, we have demonstrated that 10 ng/ml Stx2 induced DNA fragmentation in human brain microvascular endothelial...

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Bibliografski detalji
Glavni autori: Fujii, Jun, Wood, Katie, Matsuda, Fumiko, Carneiro-Filho, Benedito A., Schlegel, Keilo H., Yutsudo, Takashi, Binnington-Boyd, Beth, Lingwood, Clifford A., Obata, Fumiko, Kim, Kwang S., Yoshida, Shin-ichi, Obrig, Tom
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493216/
https://ncbi.nlm.nih.gov/pubmed/18541659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01581-07
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