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Toxicity of Shiga Toxin 1 in the Central Nervous System of Rabbits

The action of Shiga toxin (Stx) on the central nervous system was examined in rabbits. Intravenous Stx1 was 44 times more lethal than Stx2 and acted more rapidly than Stx2. However, Stx1 accumulated more slowly in the cerebrospinal fluid than did Stx2. Magnetic resonance imaging demonstrated a predo...

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Detalhes bibliográficos
Main Authors: Fujii, Jun, Kinoshita, Yoshimasa, Yutsudo, Takashi, Taniguchi, Hatsumi, Obrig, Tom, Yoshida, Shin-Ichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98795/
https://ncbi.nlm.nih.gov/pubmed/11553604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.10.6545-6548.2001
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