Toxicity of Shiga Toxin 1 in the Central Nervous System of Rabbits

The action of Shiga toxin (Stx) on the central nervous system was examined in rabbits. Intravenous Stx1 was 44 times more lethal than Stx2 and acted more rapidly than Stx2. However, Stx1 accumulated more slowly in the cerebrospinal fluid than did Stx2. Magnetic resonance imaging demonstrated a predo...

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Bibliografiske detaljer
Main Authors: Fujii, Jun, Kinoshita, Yoshimasa, Yutsudo, Takashi, Taniguchi, Hatsumi, Obrig, Tom, Yoshida, Shin-Ichi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC98795/
https://ncbi.nlm.nih.gov/pubmed/11553604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.10.6545-6548.2001
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