A mutant poliovirus containing a novel proteolytic cleavage site in VP3 is altered in viral maturation.

A six-amino-acid insertion containing a Q-G amino acid pair was introduced into the carboxy terminus of the capsid protein VP3 (between residues 236 and 237). Transfection of monkey cells with full-length poliovirus cDNA containing the insertion described above yields a mutant virus (Sel-1C-02) in w...

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Pubblicato in:	J Virol
Autori principali:	Blair, W S, Hwang, S S, Ypma-Wong, M F, Semler, B L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249316/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2157059/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.4.1784-1793.1990
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