Fibroblast growth factor represses Smad-mediated myofibroblast activation in aortic valvular interstitial cells

This study aimed to identify signaling pathways that oppose connective tissue fibrosis in the aortic valve. Using valvular interstitial cells (VICs) isolated from porcine aortic valve leaflets, we show that basic fibroblast growth factor (FGF-2) effectively blocks transforming growth factor-β1 (TGF-...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cushing, Melinda C., Mariner, Peter D., Liao, Jo-Tsu, Sims, Evan A., Anseth, Kristi S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Federation of American Societies for Experimental Biology 2008
Gaiak:
Research Communications
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493079/
https://ncbi.nlm.nih.gov/pubmed/18218921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.07-087627
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak