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Myofibroblastic activation of valvular interstitial cells is modulated by spatial variations in matrix elasticity and its organization
Valvular interstitial cells (VICs) are key regulators of the heart valve’s extracellular matrix (ECM), and upon tissue damage, quiescent VIC fibroblasts become activated to myofibroblasts. As the behavior of VICs during disease progression and wound healing is different compared to healthy tissue, w...
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| Publicado no: | Biomaterials |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5452973/ https://ncbi.nlm.nih.gov/pubmed/28390245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.03.040 |
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