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Oncolytic adenoviral mutants induce a novel mode of programmed cell death in ovarian cancer
Oncolytic adenoviral mutants have considerable activity in ovarian cancer. However, the mechanisms by which they induce cell death remain uncertain. dl922-947, which contains a 24 bp deletion in E1A CR2, is more potent than both E1A wild-type adenoviruses and the E1B-55K deletion mutant dl1520 (Onyx...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2493060/ https://ncbi.nlm.nih.gov/pubmed/18071311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210977 |
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