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Oncolytic adenoviral mutants induce a novel mode of programmed cell death in ovarian cancer

Oncolytic adenoviral mutants have considerable activity in ovarian cancer. However, the mechanisms by which they induce cell death remain uncertain. dl922-947, which contains a 24 bp deletion in E1A CR2, is more potent than both E1A wild-type adenoviruses and the E1B-55K deletion mutant dl1520 (Onyx...

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Библиографические подробности
Главные авторы: Baird, SK, Aerts, JL, Eddaoudi, A, Lockley, M, Lemoine, NR, McNeish, IA
Формат: Artigo
Язык:Inglês
Опубликовано: 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493060/
https://ncbi.nlm.nih.gov/pubmed/18071311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210977
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