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Tissue transglutaminase modulates α-synuclein oligomerization

We have studied the interaction of the enzyme tissue transglutaminase (tTG), catalyzing cross-link formation between protein-bound glutamine residues and primary amines, with Parkinson's disease-associated α-synuclein protein variants at physiologically relevant concentrations. We have, for the...

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Bibliographic Details
Main Authors: Segers-Nolten, Ine M.J., Wilhelmus, Micha M.M., Veldhuis, Gertjan, van Rooijen, Bart D., Drukarch, Benjamin, Subramaniam, Vinod
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492824/
https://ncbi.nlm.nih.gov/pubmed/18505736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.036103.108
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