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Parkinson’s Protein α-Synuclein Binds Efficiently and with a Novel Conformation to Two Natural Membrane Mimics

Binding of human α-Synuclein, a protein associated with Parkinson’s disease, to natural membranes is thought to be crucial in relation to its pathological and physiological function. Here the binding of αS to small unilamellar vesicles mimicking the inner mitochondrial and the neuronal plasma membra...

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發表在:PLoS One
Main Authors: Kumar, Pravin, Segers-Nolten, Ine M. J., Schilderink, Nathalie, Subramaniam, Vinod, Huber, Martina
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654490/
https://ncbi.nlm.nih.gov/pubmed/26588454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142795
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